Endodiabesity

A selection of highlights and headlines from BES 2023:

• [11C] Metomidate PET-CT compared to adrenal vein sampling for diagnosing primary aldosteronism

[11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial | Nature Medicine

• [¹⁸F]AldoView  –  Aldosterone Synthase PET Tracer – a novel, highly selective tracer for imaging of Primary Hyperaldosteronism

Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism | Journal of Medicinal Chemistry (acs.org)

• Hypertonic Saline- stimulated Copeptin appears more accurate that arginine-stimulated copeptin for AVP deficiency

Arginine or Hypertonic Saline–Stimulated Copeptin to Diagnose AVP Deficiency | NEJM

• Urine Tests for identifying Endocrine Hypertension

Urine steroid metabolomics as a diagnostic tool in endocrine hypertension | SFEBES2023 | Society for Endocrinology BES 2023 | Endocrine Abstracts (endocrine-abstracts.org)

• Single dose of zolendronic acid appears effective for paget’s prevention  – ZiPP study

https://www.endocrine-abstracts.org/ea/0094/ea0094p31

• Long term antithyroid treatment compared to Surgery/RAI (virtual thyroid clinic)

Audit of long-term treatment outcomes of thyrotoxicosis in a single-centre virtual clinic: The utility of long-term antithyroid drugs – PubMed (nih.gov)

PRAGMA study (post radioiodine graves disease management)

https://onlinelibrary.wiley.com/doi/10.1111/cen.14719

• Sir Mark Caulfield – Transforming Genomics in Healthcare (President’s lecture)

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(19)31796-9/fulltext

• Ewan Pearson – Precision Medicine in Diabetes and  diabetes subtyping based on clinical variables

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9522818/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8382625/

https://onlinelibrary.wiley.com/doi/10.1111/dme.14449

• How do we and should we follow up micro NFPAs?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9908737/

https://academic.oup.com/ejendo/article/189/1/87/7204866?login=false

• A new name for NAFLD – meet “MASLD” ( Metabolic dysfunction-associated steatotic liver disease)

https://journals.lww.com/hep/pages/articleviewer.aspx?year=9900&issue=00000&article=00488&type=Fulltext

• Liver function abnormalities and fibrosis in patients with Turner syndrome

https://academic.oup.com/jcem/article-abstract/108/9/2255/7075202?redirectedFrom=fulltext&login=false

Look out for:

• Society for Endocrinology guidelines for the treatment of female hypogonadism